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Title: | Gene discovery in Triatoma infestans | Authors: | Avila, Maria L. Tekiel, Valeria Moretti, Georgina Nicosia, Soledad Bua, Jacqueline Lammel, Estela M. Stroppa, Maria M. Gerez de Burgos, Nelia M. Sanchez, Daniel O. |
Issue Date: | 2011 | Description: | Background: Triatoma infestans is the most relevant vector of Chagas disease in the southern cone of South America. Since its genome has not yet been studied, sequencing of Expressed Sequence Tags ( ESTs) is one of the most powerful tools for efficiently identifying large numbers of expressed genes in this insect vector. Results: In this work, we generated 826 ESTs, resulting in an increase of 47% in the number of ESTs available for T. infestans. These ESTs were assembled in 471 unique sequences, 151 of which represent 136 new genes for the Reduviidae family. Conclusions: Among the putative new genes for the Reduviidae family, we identified and described an interesting subset of genes involved in development and reproduction, which constitute potential targets for insecticide development. |
URI: | http://sgc.anlis.gob.ar/handle/123456789/493 | Rights: | openAccess |
Appears in Collections: | Preproducción Publicaciones INP |
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File | Description | Size | Format | |
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Parasites&Vectors,2011,4,39..pdf | 690.53 kB | Adobe PDF | View/Open |
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