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|Title:||Human Polymorphisms in Placentally Expressed Genes and Their Association With Susceptibility to Congenital Trypanosoma cruzi Infection||Authors:||Juiz, Natalia A.
Cayo, Nelly M.
Salvo, Miriam E
Nasser, Julio R.
Longhi, Silvia A
Schijman, Alejandro G.
|Keywords:||Chagas congénita;Proteína ADAM12;ALPP;Metaloproteinasa 2 de la Matriz;Metaloproteinasa 9 de la Matriz;Polimorfismo de Nucleótido Simple||Issue Date:||15-Apr-2016||Journal:||The Journal of infectious diseases||Abstract:||It is currently unclear why only a proportion of children born to Trypanosoma cruzi-infected mothers acquire the infection. We have examined the association of 11 single-nucleotide polymorphisms (SNPs) located in genes coding for placental expression enzymes as genetic markers of susceptibility to congenital T. cruzi infection (hereafter, "congenital infection"): rs2014683 and rs1048988 in ALPP; rs11244787 and rs1871054 in ADAM12; rs243866, rs243865, rs17859821, rs243864, and rs2285053 in MMP2; and rs3918242 and rs2234681 in MMP9.||URI:||http://sgc.anlis.gob.ar/handle/123456789/1432||DOI:||10.1093/infdis/jiv561|
|Appears in Collections:||Publicaciones INP|
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