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Title: | Prognostic significance of α- and β2-adrenoceptor gene expression in breast cancer patients | Authors: | Rivero, Ezequiel Mariano Martinez, Leandro Marcelo Bruque, Carlos David Gargiulo, Lucia Bruzzone, Ariana Lüthy, Isabel Alicia |
Keywords: | Pronóstico;Neoplasias de la Mama;Neoplasias | Issue Date: | Sep-2019 | Publisher: | British Pharmacological Society | Journal: | British journal of clinical pharmacology | Abstract: | Breast cancer is the most frequently diagnosed and leading cause of cancer death among women worldwide. It was classified within molecular intrinsic subtypes: luminal A, luminal B, human epidermal growth factor receptor 2-enriched and basal-like. Epinephrine and norepinephrine, released during stress, bind to adrenoceptors. α2 -adrenoceptors are encoded by the ADRA2A, ADRA2B and ADRA2C genes and β2 by ADRB2. |
Description: | Fil: Rivero, Ezequiel Mariano. Laboratory of Hormones and Cancer, Instituto de Biología y Medicina Experimental (IBYME) - CONICET, Ciudad Autónoma de Buenos Aires; Argentina. Fil: Martinez, Leandro Marcelo. Research Institute, Hospital for Special Surgery, New York; Estados Unidos. Fil: Bruque, Carlos David. ANLIS Dr.C.G.Malbrán. Centro Nacional de Genética Médica; Argentina. Fil: Gargiulo, Lucia. Laboratory of Hormones and Cancer, Instituto de Biología y Medicina Experimental (IBYME) - CONICET, Ciudad Autónoma de Buenos Aires; Argentina. Fil: Bruzzone, Ariana. Instituto de Investigaciones Bioquímicas Bahía Blanca INIBIBB-CONICET, Bahía Blanca; Argentina. Fil: Lüthy, Isabel Alicia. Laboratory of Hormones and Cancer, Instituto de Biología y Medicina Experimental (IBYME) - CONICET, Ciudad Autónoma de Buenos Aires; Argentina. |
URI: | http://sgc.anlis.gob.ar/handle/123456789/1322 | DOI: | 10.1111/bcp.14030 | Rights: | Open Access |
Appears in Collections: | Publicaciones CeNaGeM |
Files in This Item:
File | Description | Size | Format | |
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10.1111_bcp.14030..pdf | Artículo en inglés | 2.28 MB | Adobe PDF | View/Open |
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