Please use this identifier to cite or link to this item: http://sgc.anlis.gob.ar/handle/123456789/424
Title: Molecular epidemiology of vancomycin-resistant Enterococcus faecium in Argentina
Authors: Corso, Alejandra 
Gagetti, Paula 
Rodríguez, Marisa M. 
Melano, Roberto 
Ceriana, Paola G. 
Faccone, Diego 
Galas, Marcelo F. 
The VRE Argentinean Collaborative Group 
Keywords: Enterococcus faecium;Epidemiología Molecular;Resistencia a la Vancomicina;Argentina
Issue Date: 2007
Description: OBJECTIVE To characterize the mechanism of glycopeptide resistance and to determine the genetic relatedness among strains by pulsed-field gel electrophoresis (PFGE) in vancomycin-resistant Enterococcus faecium from Argentina. MATERIALS AND METHODS A total of 189 vancomycin-resistant single-patient isolates of Enterococcus faecium recovered between January 1997 and December 2000 from 30 hospitals in Argentina were studied. Minimum inhibitory concentrations were determined by the agar dilution method and van genes were detected by PCR. PFGE was used for molecular typing. RESULTS All isolates except three (vanB) were of genotype vanA. For 189 vancomycin-resistant Enterococcus faecium, SmaI-PFGE indicated 35 clonal types. Most of the isolates (56%) belonged to the same clonal type 1, which was present in 19 hospitals and dominant in 17. CONCLUSIONS The emergence of vancomycin-resistant Enterococcus faecium in Argentina seems to be related to the intra- and inter-hospital dissemination of an epidemic clone carrying the vanA element.
Fil: Corso, Alejandra. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Servicio Antimicrobianos; Argentina.
Fil: Gagetti, Paula. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Servicio Antimicrobianos; Argentina.
Fil: Rodríguez, Marisa M. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Servicio Antimicrobianos; Argentina.
Fil: Melano, Roberto. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Servicio Antimicrobianos; Argentina.
Fil: Ceriana, Paola G. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Servicio Antimicrobianos; Argentina.
Fil: Faccone, Diego. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Servicio Antimicrobianos; Argentina.
Fil: Galas, Marcelo F. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Servicio Antimicrobianos; Argentina.
Fil: The VRE Argentinean Collaborative Group; Argentina.
URI: http://download.journals.elsevierhealth.com/pdfs/journals/1201-9712/PIIS1201971206000476.pdf
http://sgc.anlis.gob.ar/handle/123456789/424
ISSN: 1201-9712
Rights: 2008-01-31
info:eu-repo/semantics/embargoedAccess
Appears in Collections:Publicaciones INEI
snrd

Files in This Item:
File Description SizeFormat
InternationalJournalofInfectiousDiseases,2007,11(1),69-75.pdfPDF1.87 MBAdobe PDFThumbnail
View/Open
Show full item record

Page view(s)

3
checked on Sep 21, 2019

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.