Please use this identifier to cite or link to this item: http://sgc.anlis.gob.ar/handle/123456789/361
Title: Application of variable number of tandem repeats typing to describe familial outbreaks of brucellosis in Argentina
Authors: Lucero, Nidia E. 
Tenenbaum, Marina 
Jacob, Néstor R. 
Escobar, Gabriela I. 
Groussaud, Pauline 
Whatmore, Adrian M. 
Keywords: Brucelosis;Secuencias Repetidas en Tandem;Argentina;Enfermedades Transmitidas por los Alimentos
Issue Date: 2010
Description: Consumption of inadequately pasteurized dairy products is the most common means of transmission of brucellosis. This report describes two foodborne outbreaks that occurred in families infected after consumption of fresh home-made cheese bought in different Argentine provinces. High resolution variable number of tandem repeats (VNTR)-based analysis revealed two well-defined groups comprising essentially identical profiles and corresponding to the two different outbreaks. Similar clinical findings in members of the same family could indicate that the differential virulence of different bacterial clones, as indicated by VNTR data, could have influenced the course of the disease. We observed the importance of adequate treatment in early stages of the disease; combination therapy and extended treatment for 6 weeks or longer yielded significantly better results. The risk of the foodborne transmission of this zoonotic disease and disease prevention should be considered.
Fil: Lucero, Nidia E. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Laboratorio de Brucelosis; Argentina.
Fil: Jacob, Néstor R. Hospital Dr. Cosme Argerich. Departamento de Infectologia; Argentina.
Fil: Tenenbaum, Marina. Hospital de Pediatria Dr. Ricardo Gutierrez. Departamento de Infectologia; Argentina.
Fil: Escobar, Gabriela I. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Laboratorio de Brucelosis; Argentina.
Fil: Groussaud, Pauline. Veterinary Laboratories Agency. Department of Statutory and Exotic Bacterial Diseases. Brucellosis Reference Unit; Reino Unido.
URI: http://jmm.sgmjournals.org/content/59/6/648.full.pdf
http://sgc.anlis.gob.ar/handle/123456789/361
ISSN: 0022-2615
Rights: 2011-06-30
info:eu-repo/semantics/embargoedAccess
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