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Title: | PulseNet International Survey on the Implementation of Whole Genome Sequencing in Low and Middle-Income Countries for Foodborne Disease Surveillance | Authors: | Davedow, Taylor Carleton, Heather Kubota, Kristy Palm, Daniel Schroeder, Morgan Gerner-Smidt, Peter Al-Jardani, Amina Chinen, Isabel Kam, Kai Man Smith, Anthony M Nadon, Celine |
Keywords: | PulseNet;Enfermedades Transmitidas por los Alimentos;Vigilancia;Secuenciación Completa del Genoma | Issue Date: | May-2022 | Journal: | Foodborne pathogens and disease | Abstract: | PulseNet International (PNI) is a global network of 88 countries who work together through their regional and national public health laboratories to track foodborne disease around the world. The vision of PNI is to implement globally standardized surveillance using whole genome sequencing (WGS) for real-time identification and subtyping of foodborne pathogens to strengthen preparedness and response and lower the burden of disease. Several countries in North America and Europe have experienced significant benefits in disease mitigation after implementing WGS. To broaden the routine use of WGS around the world, challenges and barriers must be overcome. We conducted this study to determine the challenges and barriers countries are encountering in their attempts to implement WGS and to identify how PNI can provide support to improve and become a better integrated system overall. A survey was designed with a set of qualitative questions to capture the status, challenges, barriers, and successes of countries in the implementation of WGS and was administered to laboratories in Africa, Asia-Pacific, Latin America and the Caribbean, and Middle East. One-third of respondents do not use WGS, and only 8% reported using WGS for routine, real-time surveillance. The main barriers for implementation of WGS were lack of funding, gaps in expertise, and training, especially for data analysis and interpretation. Features of an ideal system to facilitate implementation and global surveillance were identified as an all-in-one software that is free, accessible, standardized and validated. This survey highlights the minimal use of WGS for foodborne disease surveillance outside the United States, Canada, and Europe to date. Although funding remains a major barrier to WGS-based surveillance, critical gaps in expertise and availability of tools must be overcome. Opportunities to seek sustainable funding, provide training, and identify solutions for a globally standardized surveillance platform will accelerate implementation of WGS worldwide. |
Description: | Fil: Davedow, Taylor. Division of Enteric Diseases, Public Health Agency of Canada, National Microbiology Laboratory; Canada Fil: Carleton, Heather. Centers for Disease Control and Prevention, Atlanta; United States Fil: Kubota, Kristy. Association of Public Health Laboratories; United States Fil: Palm, Daniel. European Centre for Disease Prevention and Control; Suecia Fil: Schroeder, Morgan. Centers for Disease Control and Prevention, Atlanta; United States Fil: Gerner-Smidt, Peter. Centers for Disease Control and Prevention, Atlanta; United States Fil: Al-Jardani, Amina. Central Public Health Laboratories, Ministry of Health; Oman Fil: Chinen, Isabel. Instituto Nacional de Enfermedades Infecciosas, Administracion Nacional del Laboratorios et Institutos de Salud "Dr. Carlos G. Malbrán," Ciudad Autónoma de Buenos Aires; Buenos Aires, Argentina Fil: Kam, Kai Man. Stanley Ho Centre for Emerging Infectious Diseases, School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong; China Fil: Smith, Anthony M. National Institute for Communicable Diseases; Sudáfrica Fil: Nadon, Celine. Department of Medical Microbiology and Infectious Diseases, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba; Canada |
URI: | http://sgc.anlis.gob.ar/handle/123456789/2509 | DOI: | 10.1089/fpd.2021.0110 |
Appears in Collections: | Artículos |
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fpd.2021.0110.pdf | 764.78 kB | Adobe PDF | View/Open |
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