Please use this identifier to cite or link to this item:
|Title:||Shiga toxin 2 from enterohemorrhagic Escherichia coli induces reactive glial cells and neurovascular disarrangements including edema and lipid peroxidation in the murine brain hippocampus||Authors:||Berdasco, Clara
Geoghegan, Patricia A.
|Keywords:||Encefalopatía;Hipocampo;Peroxidación de Lípido||Issue Date:||7-Feb-2019||Journal:||Journal of biomedical science||Abstract:||
Shiga toxin 2 from enterohemorrhagic Escherichia coli is the etiologic agent of bloody diarrhea, hemolytic uremic syndrome and derived encephalopathies that may result to death in patients. Being a Gram negative bacterium, lipopolysaccharide is also released. Particularly, the hippocampus has been found affected in patients intoxicated with Shiga toxin 2. In the current work, the deleterious effects of Shiga toxin 2 and lipopolysaccharide are investigated in detail in hippocampal cells for the first time in a translational murine model, providing conclusive evidences on how these toxins may damage in the observed clinic cases.
|Appears in Collections:||Publicaciones CNCCB|
Show full item record
Files in This Item:
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.