Please use this identifier to cite or link to this item: http://sgc.anlis.gov.ar/handle/123456789/1445
Title: Elucidating the impact of low doses of nano-formulated benznidazole in acute experimental Chagas disease
Authors: Rial, Marcela Silvina 
Scalise, María L 
Arrúa, Eva C 
Esteva, Monica I 
Salomon, Claudio J 
Fichera, Laura E. 
Issue Date: 2017
Journal: PLoS neglected tropical diseases 
Abstract: 
Chagas disease is a neglected parasitic infection caused by the protozoan Trypanosoma cruzi (T. cruzi) that affects more than 6 million people, mainly in Latin America. Benznidazole is still the drug of choice in many countries to treat it in spite of its dosage regimen and adverse side effects such as such as allergic dermatitis, peripheral neuropathy and anorexia. Thus, novel, safer, and more efficacious treatments for such neglected infection are urgently required.
URI: http://sgc.anlis.gob.ar/handle/123456789/1445
DOI: 10.1371/journal.pntd.0006119
Appears in Collections:Publicaciones INP

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