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Title: The Significance of Discordant Serology in Chagas Disease: Enhanced T-Cell Immunity to Trypanosoma cruzi in Serodiscordant Subjects
Authors: Castro Eiro, Melisa D 
Alvarez, María G 
Cooley, Gretchen 
Viotti, Rodolfo J 
Bertocchi, Graciela L 
Lococo, Bruno 
Albareda, María C 
De Rissio, Ana María 
Natale, María A 
Parodi, Cecilia 
Tarleton, Rick L 
Laucella, Susana A. 
Keywords: T cells;Trypanosoma cruzi;ensayo multiplex;polifuncionalidad;serodiscordancia
Issue Date: 2017
Journal: Frontiers in immunology 
Abstract: Subjects are considered infected with Trypanosoma cruzi when tested positive by at least two out of three serological tests, whereas a positive result in only one of up to three tests is termed "serodiscordant" (SD). Assessment of parasite-specific T-cell responses may help discriminate the uninfected from infected individuals among SD subjects.
ISSN: 1664-3224
DOI: 10.3389/fimmu.2017.01141
Appears in Collections:Publicaciones INP

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