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Title: Treatment Success in Trypanosoma cruzi Infection Is Predicted by Early Changes in Serially Monitored Parasite-Specific T and B Cell Responses
Authors: Alvarez, María G 
Bertocchi, Graciela L 
Cooley, Gretchen 
Albareda, María C 
Viotti, Rodolfo 
Pérez-Mazliah, Damián E 
Lococo, Bruno 
Castro Eiro, Melisa D 
Laucella, Susana A. 
Tarleton, Rick L 
Issue Date: Apr-2016
Journal: PLoS neglected tropical diseases 
Chagas disease is the highest impact parasitic disease in Latin America. We have proposed that changes in Trypanosoma cruzi-specific immune responses might serve as surrogate indicators of treatment success. Herein, we addressed in a long-term follow-up study whether cure achieved after treatment can be predicted by changes in non-conventional indexes of anti-parasite serological and T cell activities.
DOI: 10.1371/journal.pntd.0004657
Appears in Collections:Publicaciones INP

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