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http://sgc.anlis.gob.ar/handle/123456789/1426| Title: | Treatment Success in Trypanosoma cruzi Infection Is Predicted by Early Changes in Serially Monitored Parasite-Specific T and B Cell Responses | Authors: | Alvarez, María G Bertocchi, Graciela Luciana Cooley, Gretchen Albareda, María Cecilia Viotti, Rodolfo Pérez-Mazliah, Damián E Lococo, Bruno Castro Eiro, Melisa D Laucella, Susana A. Tarleton, Rick L |
Keywords: | Enfermedad de Chagas;Trypanosoma cruzi;América Latina | Issue Date: | 29-Apr-2016 | Publisher: | Yes | Journal: | PLoS neglected tropical diseases | Abstract: | Chagas disease is the highest impact parasitic disease in Latin America. We have proposed that changes in Trypanosoma cruzi-specific immune responses might serve as surrogate indicators of treatment success. Herein, we addressed in a long-term follow-up study whether cure achieved after treatment can be predicted by changes in non-conventional indexes of anti-parasite serological and T cell activities. |
Description: | Fil: Alvarez, María G. Hospital Interzonal General de Agudos Eva Perón, Buenos Aires; Argentina. Fil: Bertocchi, Graciela Luciana. Hospital Interzonal General de Agudos Eva Perón, Buenos Aires; Argentina. Fil: Cooley, Gretchen. Center for Tropical and Emerging Global Diseases, Athens, Georgia; Estados Unidos. Fil: Albareda, María Cecilia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina. Fil: Viotti, Rodolfo. Hospital Interzonal General de Agudos Eva Perón, Buenos Aires; Argentina. Fil: Pérez-Mazliah, Damián E. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina. Fil: Lococo, Bruno. Hospital Interzonal General de Agudos Eva Perón, Buenos Aires; Argentina. Fil: Castro Eiro, Melisa D. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina. Fil: Laucella, Susana A. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina. Fil: Tarleton, Rick L. Center for Tropical and Emerging Global Diseases, Athens, Georgia; Estados Unidos. |
URI: | http://sgc.anlis.gob.ar/handle/123456789/1426 | ISSN: | 1935-2735 | DOI: | 10.1371/journal.pntd.0004657 | Rights: | Open Access |
| Appears in Collections: | Publicaciones INP |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| pntd.0004657.pdf | Artículo en inglés | 1.29 MB | Adobe PDF |  View/Open |
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