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Title: Widespread geographic distribution of oral Candida dubliniensis strains in human immunodeficiency virus-infected individuals
Authors: Sullivan, Derek 
Haynes, Ken 
Bille, Jacques 
Boerlin, Patrick 
Rodero, Laura 
Lloyd, Siobhán 
Henman, Martin 
Coleman, David 
Keywords: Candida;Candidiasis Bucal;Infecciones Oportunistas Relacionadas con SIDA;ADN de Hongos;VIH-1
Issue Date: 1997
Description: Candida dubliniensis is a recently identified chlamydospore-positive yeast species associated with oral candidiasis in human immunodeficiency virus (HIV)-infected (HIV1) patients and is closely related to Candida albicans. Several recent reports have described atypical oral Candida isolates with phenotypic and genetic properties similar to those of C. dubliniensis. In this study 10 atypical chlamydospore-positive oral isolates from HIV1 patients in Switzerland, the United Kingdom, and Argentina and 1 isolate from an HIV-negative Irish subject were compared to reference strains of C. albicans and Candida stellatoidea and reference strains of C. dubliniensis recovered from Irish and Australian HIV1 individuals. All 11 isolates were phenotypically and genetically similar to and phylogenetically identical to C. dubliniensis. These findings demonstrate that the geographical distribution of C. dubliniensis is widespread, and it is likely that it is a significant constituent of the normal oral flora with the potential to cause oral candidiasis, particularly in immunocompromised patients.
Fil: Sullivan, Derek. University of Dublin. Department of Oral Medicine and Pathology; Irlanda.
Fil: Bille, Jacques.
Fil: Haynes, Ken. Hammersmith Hospital. Department of Infectious Diseases and Bacteriology; Reino Unido.
Fil: Bille, Jacques. University Hospital. Institute of Microbiology; Suiza.
Fil: Rodero, Laura. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Microbiología; Argentina.
Fil: Lloyd, Siobhán. University of Dublin. Department of Oral Medicine and Pathology; Irlanda.
Fil: Henman, Martin. University of Dublin. Department of Pharmacology; Irlanda.
Fil: Coleman, David. University of Dublin. Department of Oral Medicine and Pathology; Irlanda.
ISSN: 1098-660X
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:Publicaciones INEI

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