Please use this identifier to cite or link to this item: http://sgc.anlis.gob.ar/handle/123456789/275
Title: Emergence of a Streptococcus pneumoniae clinical isolate highly resistant to telithromycin and fluoroquinolones
Authors: Faccone, Diego 
Andres, Patricia 
Galas, Marcelo F. 
Tokumoto, Marta 
Rosato, Adriana 
Corso, Alejandra 
Keywords: Streptococcus pneumoniae;Fluoroquinolonas;Farmacorresistencia Bacteriana Múltiple;Infecciones Neumocócicas
Issue Date: 2005
Description: Streptococcus pneumoniae is a major pathogen causing community-acquired pneumonia and acute bronchitis. Macrolides, fluoroquinolones (FQs), and, recently, telithromycin (TEL) constitute primary therapeutic options, and rare cases of resistance have been reported. In this report, we describe the emergence of an S. pneumoniae clinical isolate with high-level TEL resistance (MIC, 256 g/ml) and simultaneous resistance to FQs. Ongoing studies are oriented to elucidate the precise mechanism of resistance to TEL.
Fil: Faccone, Diego. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Antimicrobianos; Argentina.
Fil: Andres, Patricia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Antimicrobianos; Argentina.
Fil: Galas, Marcelo F. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Antimicrobianos; Argentina.
Fil: Tokumoto, Marta. Fundación Favaloro. Servicio de Microbiología; Argentina.
Fil: Rosato, Adriana. Virginia Commonwealth University. Division of Infectious Diseases; Estados Unidos.
Fil: Corso, Alejandra. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Antimicrobianos; Argentina.
URI: http://jcm.asm.org/content/43/11/5800.full.pdf+html
http://sgc.anlis.gob.ar/handle/123456789/275
ISSN: 1098-660X
Rights: info:eu-repo/semantics/openAccess
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