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http://sgc.anlis.gob.ar/handle/123456789/275| Title: | Emergence of a Streptococcus pneumoniae clinical isolate highly resistant to telithromycin and fluoroquinolones | Authors: | Faccone, Diego Andres, Patricia Galas, Marcelo F. Tokumoto, Marta Rosato, Adriana Corso, Alejandra |
Keywords: | Streptococcus pneumoniae;Fluoroquinolonas;Farmacorresistencia Bacteriana Múltiple;Infecciones Neumocócicas | Issue Date: | 2005 | Description: | Streptococcus pneumoniae is a major pathogen causing community-acquired pneumonia and acute bronchitis. Macrolides, fluoroquinolones (FQs), and, recently, telithromycin (TEL) constitute primary therapeutic options, and rare cases of resistance have been reported. In this report, we describe the emergence of an S. pneumoniae clinical isolate with high-level TEL resistance (MIC, 256 g/ml) and simultaneous resistance to FQs. Ongoing studies are oriented to elucidate the precise mechanism of resistance to TEL. Fil: Faccone, Diego. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Antimicrobianos; Argentina. Fil: Andres, Patricia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Antimicrobianos; Argentina. Fil: Galas, Marcelo F. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Antimicrobianos; Argentina. Fil: Tokumoto, Marta. Fundación Favaloro. Servicio de Microbiología; Argentina. Fil: Rosato, Adriana. Virginia Commonwealth University. Division of Infectious Diseases; Estados Unidos. Fil: Corso, Alejandra. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Antimicrobianos; Argentina. |
URI: | http://sgc.anlis.gob.ar/handle/123456789/275 http://jcm.asm.org/content/43/11/5800.full.pdf+html |
ISSN: | 1098-660X | Rights: | info:eu-repo/semantics/openAccess |
| Appears in Collections: | snrd Publicaciones INEI |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| JournalofClinicalMicrobiology,2005,43(11),5800–5803..pdf | 101.8 kB | Adobe PDF |  View/Open |
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