Please use this identifier to cite or link to this item: http://sgc.anlis.gob.ar/handle/123456789/271
Title: Population structure and diversity of the pathogenic fungus Aspergillus fumigatus isolated from different sources and geographic origins
Authors: Duarte-Escalante, Esperanza 
Zúñiga, Gerardo 
Nava Ramírez, Oscar 
Córdoba, Susana 
Refojo, Nicolás 
Arenas, Roberto 
Delhaes, Laurence 
Reyes-Montes, María del Rocío 
Keywords: Aspergillus fumigatus;Análisis del Polimorfismo de Longitud de Fragmentos Amplificados;Variación Genética
Issue Date: 2009
Description: Fifty-five clinical and environmental Aspergillus fumigatusisolates from Mexico, Argentina, France and Peru were analyzed to determine their genetic variability, reproductive system and level of differentiation using amplified fragment length polymorphismmarkers. The level of genetic variability was assessed by measuring the percentage of polymorphic loci, number of effective alleles, expected heterozygocity and by performing an association index test (I A ). The degree of genetic differentiation and variation was determined using analysis of molecular variance at three levels. Using the paired genetic distances, a dendrogram was built to detect the genetic relationship among alleles. Finally, a network of haplotypes was constructed to determine the geographic relationship among them. The results indicate that the clinical isolates have greater genetic variability than the environmental isolates. The I A of the clinical and environmental isolates suggests a recombining population structure. The genetic differentiation among isolates and the dendrogram suggest that the groups of isolates are different. The network of haplotypes demonstrates that the majority of the isolates are grouped according to geographic origin.
Fil: Duarte-Escalante, Esperanza. Universidad Nacional Autónoma de México. Laboratorio de Micología Molecular; México.
Fil: Zúñiga, Gerardo. Instituto Politécnico Nacional. Departamento de Zoología; México.
Fil: Nava Ramírez, Oscar. Universidad Nacional Autónoma de México. Laboratorio de Micología Molecular; México.
Fil: Córdoba, Susana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Departamento Micología; Argentina.
Fil: Refojo, Nicolás. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Departamento Micología; Argentina.
Fil: Arenas, Roberto. Hospital General Dr. Manuel Gea González; México.
Fil: Delhaes, Laurence. Pasteur Institute of Lille; Francia.
Fil: Reyes-Montes, María del Rocío. Universidad Nacional Autónoma de México. Laboratorio de Micología Molecular; México.
URI: http://www.scielo.br/pdf/mioc/v104n3/05.pdf
http://sgc.anlis.gob.ar/handle/123456789/271
ISSN: 0074-0276
Rights: info:eu-repo/semantics/openAccess
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