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Title: | Can We Use Imipenem and Meropenem Vitek 2 MICs for Detection of Suspected KPC and Other-Carbapenemase Producers among Species of Enterobacteriaceae? | Authors: | Pasteran, Fernando Lucero, Celeste Soloaga, Rolando Rapoport, Melina J. Corso, Alejandra |
Keywords: | Antibacterianos;Proteínas Bacterianas;beta-Lactamasas;Enterobacteriaceae;Imipenem;Humanos;Pruebas de Sensibilidad Microbiana;Sensibilidad y Especificidad;Tienamicinas | Issue Date: | 2011 | Journal: | Journal of clinical microbiology | Abstract: | Imipenem and meropenem Vitek 2 MICs were evaluated for a panel of 104 Enterobacteriaceae for identification of carbapenemase producers. The sensitivity and specificity values for the new CLSI interpretative criteria (CLSI document M100-S20-U, 2010) were 98% and 83% for imipenem and 76% and 83% for meropenem, respectively. We propose an algorithm that is highly sensitive (98%) and specific (94%) for carbapenemase screening based on the combined use of imipenem and meropenem MICs. |
Description: | Fil: Pasteran, Fernando. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Antimicrobianos; Argentina. Fil: Lucero, Celeste. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Antimicrobianos; Argentina. Fil: Soloaga, Rolando. Hospital Naval Buenos Aires Cirujano Mayor Pedro Mallo. Servicio de Microbiología; Argentina. Fil: Rapoport, Melina J. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Antimicrobianos; Argentina. Fil: Corso, Alejandra. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Antimicrobianos; Argentina. |
URI: | http://sgc.anlis.gob.ar/handle/123456789/264 http://jcm.asm.org/content/49/2/697.full.pdf+html |
ISSN: | 1098-660X | Rights: | Open Access Creative Commons Attribution 4.0 International License |
Appears in Collections: | snrd Publicaciones INEI |
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JournalofClinicalMicrobiology,2011,49(2),697–701..pdf | 519.53 kB | Adobe PDF | ![]() View/Open |
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