Please use this identifier to cite or link to this item: http://sgc.anlis.gob.ar/handle/123456789/264
Title: Can We Use Imipenem and Meropenem Vitek 2 MICs for Detection of Suspected KPC and Other-Carbapenemase Producers among Species of Enterobacteriaceae?
Authors: Pasteran, Fernando 
Lucero, Celeste 
Soloaga, Rolando 
Rapoport, Melina J. 
Corso, Alejandra 
Keywords: Antibacterianos;Proteínas Bacterianas;beta-Lactamasas;Enterobacteriaceae;Imipenem;Humanos;Pruebas de Sensibilidad Microbiana;Sensibilidad y Especificidad;Tienamicinas
Issue Date: 2011
Journal: Journal of clinical microbiology 
Abstract: 
Imipenem and meropenem Vitek 2 MICs were evaluated for a panel of 104 Enterobacteriaceae for identification of carbapenemase producers. The sensitivity and specificity values for the new CLSI interpretative criteria (CLSI document M100-S20-U, 2010) were 98% and 83% for imipenem and 76% and 83% for meropenem, respectively. We propose an algorithm that is highly sensitive (98%) and specific (94%) for carbapenemase screening based on the combined use of imipenem and meropenem MICs.
Description: 
Fil: Pasteran, Fernando. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Antimicrobianos; Argentina.

Fil: Lucero, Celeste. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Antimicrobianos; Argentina.

Fil: Soloaga, Rolando. Hospital Naval Buenos Aires Cirujano Mayor Pedro Mallo. Servicio de Microbiología; Argentina.

Fil: Rapoport, Melina J. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Antimicrobianos; Argentina.

Fil: Corso, Alejandra. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Antimicrobianos; Argentina.
URI: http://sgc.anlis.gob.ar/handle/123456789/264
http://jcm.asm.org/content/49/2/697.full.pdf+html
ISSN: 1098-660X
Rights: Open Access
Creative Commons Attribution 4.0 International License
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