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Title: | Human hydatid disease in Peru is basically restricted to Echinococcus granulosus genotype G1 | Authors: | Santivañez, Saul J. Gutierrez, Ariana M. Rosenzvit, Mara C. Muzulin, Patricia M Rodriguez, Mary L. Vasquez, Julio C. Rodriguez, Silvia Gonzalez, Armando E. Gilman, Robert H. Garcia, Héctor H. |
Keywords: | Equinococosis;Echinococcus granulosus;Zoonosis;Enfermedades de las Ovejas;Humanos;Reacción en Cadena de la Polimerasa;Genotipo;Complejo IV de Transporte de Electrones;ADN Mitocondrial;ADN de Helmintos;Perú | Issue Date: | 2008 | Description: | A molecular PCR study using DNA from 21 hydatid cysts was performed to determine which strain type is responsible for human infection in Peru. The mitochondrial cytochrome c oxidase subunit 1 (CO1) gene was amplified in 20 out of 21 samples, revealing that all but 1 sample (19/20, 95%) belonged to the common sheep strain (G1). The remaining samples belonged to the camel strain (G6). The G1 genotype was most frequently found in human cases of cystic hydatid disease (CHD) in Peru. Local control measures should focus primarily on decreasing dog and sheep infection rather than intermediate reservoirs. Fil: Santivañez, Saul J. Universidad Peruana Cayetano Heredia. Departamento de Microbiología; Perú. Fil: Gutierrez, Ariana M. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Parasitología; Argentina. Fil: Rosenzvit, Mara C. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Parasitología; Argentina. Fil: Muzulin, Patricia M. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Parasitología; Argentina. Fil: Rodriguez, Mary L. Instituto Nacional de Ciencias Neurológicas; Perú. Fil: Vasquez, Julio C. Hospital Nacional Dos de Mayo. Programa de cirugía torácica y cardiovascular; Perú. Fil: Rodriguez, Silvia. Instituto Nacional de Ciencias Neurológicas; Perú. Fil: Gonzalez, Armando E. Universidad Nacional Mayor de San Marcos. Facultad de Medicina Veterinaria; Perú. Fil: Gilman, Robert H. Johns Hopkins University. Department of International Health; Estados Unidos. Fil: Garcia, Héctor H. Universidad Peruana Cayetano Heredia. Departamento de Microbiología; Perú. |
URI: | http://sgc.anlis.gob.ar/handle/123456789/243 http://www.ajtmh.org/content/79/1/89.full.pdf+html |
ISSN: | 1476-1645 | Rights: | info:eu-repo/semantics/openAccess |
Appears in Collections: | snrd Publicaciones INEI |
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File | Description | Size | Format | |
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TheAmericanJournalofTropicalMedicineandHygiene,2008,79(1),89–92..pdf | 92.48 kB | Adobe PDF | View/Open |
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