Please use this identifier to cite or link to this item: http://sgc.anlis.gob.ar/handle/123456789/2305
Title: Los nuevos escenarios de transmisión de la fiebre hemorrágica Argentina desde la introducción de la vacuna a virus junín vivo atenuado (Candid#1): una experiencia en trabajadores golondrinas
Other Titles: New transmission scenarios of the Argentine hemorrhagic fever since the introduction of the live attenuated junin virus vaccine (Candid #1): an experience in migrant workers
Authors: Briggiler, Ana M. 
Sinchi, Anabel 
Coronel, Florencia 
Sánchez, Zaida 
Levis, Silvana 
Taylor, Jorge 
Enria, Delia 
Keywords: Fiebre Hemorrágica Americana;Virus Junin;Vaccinia;Arenavirus;Salud Pública
Issue Date: 2015
Journal: Revista peruana de medicina experimental y salud pública 
Abstract: 
The Argentine hemorrhagic fever (AHF) is a severe acute viral disease caused by the Junin virus of the Arenaviridae family. The AHF endemic area coincides geographically with the largest grain export agro-industrial complex of the country [Argentina]. Since the implementation of vaccination with the Candid #1 vaccine, a significant reduction in incidence was achieved and risk patterns were modified. A previous study allowed characterizing these changes and identifying three transmission scenarios: classic, emergent-reemergent, and traveler. The latter scenario includes seasonal migrant workers who move each year, mainly from the province of Santiago del Estero, the endemic area to work in the detasseling of maize. With the objective of protecting this group of workers, a prevention campaign was initiated which included: capacity building of health personnel in the province, health education, and immunization with the vaccine Candid #1. 3,021 workers were vaccinated. Prior to vaccination, serum samples were taken from a group of 104 volunteers. Tests for neutralizing antibodies specific to the Junin virus were performed and 6 (5.76%) tested positive. The unexpected finding of a high percentage of workers with antibodies suggests the need to evaluate several hypotheses: a) that the result is the product of non-probabilistic sampling; b) that it could be people who fell ill in previous travels, c) or who were vaccinated in previous travels; or d) consider this region as an emerging scenario.
Description: 
Fil: Briggiler, Ana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.

Fil: Sinchi, Anabel. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.

Fil: Coronel, Florencia. Ministerio de Salud de Santiago del Estero.Programa Ampliado de Inmunizaciones; Argentina.

Fil: Sánchez, Zaida. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.

Fil: Levis, Silvana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.

Fil: Taylor, Jorge. Registro Nacional de Trabajadores y Empleadores Agrarios; Argentina.

Fil: Enria, Delia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.
URI: http://sgc.anlis.gob.ar/handle/123456789/2305
http://www.scielo.org.pe/scielo.php?pid=S1726-46342015000100023&script=sci_abstract
ISSN: 1726-4634
Appears in Collections:Publicaciones INEVH

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