Please use this identifier to cite or link to this item:
http://sgc.anlis.gob.ar/handle/123456789/217
Title: | Novel variant (bla(VIM-11)) of the metallo-{beta}-lactamase bla(VIM) family in a GES-1 extended-spectrum-{beta}-lactamase-producing Pseudomonas aeruginosa clinical isolate in Argentina | Authors: | Pasteran, Fernando Faccone, Diego Petroni, Alejandro Rapoport, Melina J. Galas, Marcelo F. Vázquez, Miryam Procopio, Adriana |
Keywords: | Antibacterianos;beta-Lactamasas;Carbapenémicos;Farmacorresistencia Bacteriana;Pseudomonas aeruginosa;Infecciones por Pseudomonas;Análisis de Secuencia de ADN;Variación Genética;Argentina | Issue Date: | Jan-2005 | Journal: | Antimicrobial agents and chemotherapy | Abstract: | Two major groups of acquired β-lactamases have emerged in Pseudomonas aeruginosa: Ambler class A extended-spectrum β-lactamases (ESBLs) and class B metallo-β-lactamases (MBLs) (7, 9). MBLs are an expanding group of carbapenemases that includes the VIM family. To date, multiple allelic variants, namely, VIM-1 to VIM-10 (http://www.lahey.org/studies ), have been described in Europe, Asia, and the Americas, VIM-2 being the most ubiquitous enzyme by far (7, 8; R. E. Mendes, M. Castanheira, P. Garcia, M. Guzman, M. A. Toleman, T. R. Walsh, and R. N. Jones, Letter, Antimicrob. Agents Chemother. 48:1433-1434, 2004). Additionally, five types of ESBLs have been detected in P. aeruginosa: TEM, SHV, PER, VEB, and IBC/GES (9). Association between VIM and ESBLs still appears to be a rare event in P. aeruginosa and was reported only for VIM-2 with either PER-1 or IBC-2 (3; J. D. Docquier, J. D., F. Luzzaro, G. Amicosante, A. Toniolo, and G. M. Rossolini, Letter, Emerg. Infect. Dis. 7:910-911, 2001). MBL- or ESBL-producing P. aeruginosa isolates have not yet been reported in Argentina, while the coexistence of VIM with GES-1 in a single clinical isolate has not been documented anywhere. |
Description: | Fil: Pasteran, Fernando. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento Bacteriología. Servicio de Antimicrobianos; Argentina. Fil: Faccone, Diego. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento Bacteriología. Servicio de Antimicrobianos; Argentina. Fil: Petroni, Alejandro. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento Bacteriología. Servicio de Antimicrobianos; Argentina. Fil: Rapoport, Melina J. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento Bacteriología. Servicio de Antimicrobianos; Argentina. Fil: Galas, Marcelo F. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento Bacteriología. Servicio de Antimicrobianos; Argentina. Fil: Vázquez, Miryam. Hospital de Niños Dr. Ricardo Gutiérrez. Sección Microbiología; Argentina. Fil: Procopio, Adriana. Hospital de Niños Dr. Ricardo Gutiérrez. Sección Microbiología; Argentina. |
URI: | http://sgc.anlis.gob.ar/handle/123456789/217 http://aac.asm.org/content/49/1/474.full.pdf+html |
ISSN: | 1098-6596 | DOI: | 10.1128/AAC.49.1.474-475.2005 | Rights: | Open Access Creative Commons Attribution 4.0 International License |
Appears in Collections: | snrd Publicaciones INEI |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
AntimicrobialAgentsandChemotherapy_2005_49_1_p474–p475.pdf | 139.74 kB | Adobe PDF | View/Open |
Page view(s)
79
checked on Oct 15, 2024
Download(s)
5
checked on Oct 15, 2024
Google ScholarTM
Check
Altmetric
Altmetric
This item is licensed under a Creative Commons License