Please use this identifier to cite or link to this item:
http://sgc.anlis.gob.ar/handle/123456789/2104
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Albareda, María Cecilia | es |
dc.contributor.author | Natale, María Ailén | es |
dc.contributor.author | Cesar, Gonzalo | es |
dc.contributor.author | Castro Eiro, Melisa D | es |
dc.contributor.author | Alvarez, María Gabriela | es |
dc.contributor.author | Laucella, Susana Adriana | es |
dc.date.accessioned | 2021-01-12T17:57:59Z | - |
dc.date.available | 2021-01-12T17:57:59Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1064-3745 | - |
dc.identifier.uri | http://sgc.anlis.gob.ar/handle/123456789/2104 | - |
dc.description | Fil: Albareda, María Cecilia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina. | es |
dc.description | Fil: Natale, María Ailén. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina. | es |
dc.description | Fil: Cesar, Gonzalo Leandro. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina. | es |
dc.description | Fil: Castro Eiro, Melisa D. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina. | es |
dc.description | Fil: Alvarez, María Gabriela. Hospital Interzonal General de Agudos Eva Perón, Buenos Aires; Argentina. | es |
dc.description | Fil: Laucella, Susana Adriana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina. | es |
dc.description.abstract | Chagas disease is the highest impact parasitic disease in Latin America. In recent years, the use of immune-related biomarkers to predict diagnostic and treatment efficacy or to monitor diseases has been considered a promising tool. Our group has worked for the past 20 years on the characterization of different immunological aspects of the T-cell responses to T. cruzi antigens. We have shown that monitoring of appropriate immunological responses can provide earlier and robust measures of treatment.The Enzyme-Linked ImmunoSPOT (ELISPOT) assays are powerful tools to evaluate antigen-specific immune responses at the single-cell level. Herein, we describe uses of the ELISPOT assay to determine the T. cruzi-specific T-cell populations in PBMCs from chronic chagasic subjects. | es |
dc.language.iso | en | es |
dc.publisher | Humana Press | es |
dc.relation.ispartof | Methods in molecular biology (Clifton, N.J.) | es |
dc.rights | Closed Access | - |
dc.source | Methods in Molecular Biology 2019;1955:339-348. | - |
dc.subject | Enfermedad de Chagas | es |
dc.subject | Trypanosoma cruzi | es |
dc.title | Trypanosoma cruzi-Specific T-Cell Responses to Monitor Treatment Efficacy in Chronic Chagas Disease | es |
dc.type | Artículo | es |
dc.identifier.doi | 10.1007/978-1-4939-9148-8_25 | - |
anlis.essnrd | 1 | - |
item.grantfulltext | none | - |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.openairetype | Artículo | - |
crisitem.author.dept | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
crisitem.author.dept | Instituto Nacional de Parasitología (INP) | - |
crisitem.author.parentorg | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
Appears in Collections: | Publicaciones INP |
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