Please use this identifier to cite or link to this item:
http://sgc.anlis.gob.ar/handle/123456789/1969
DC Field | Value | Language |
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dc.contributor.author | Sahaza, Jorge H | es |
dc.contributor.author | Suárez-Alvarez, Roberto | es |
dc.contributor.author | Estrada-Bárcenas, Daniel Alfonso | es |
dc.contributor.author | Pérez-Torres, Armando | es |
dc.contributor.author | Taylor, Maria Lucia | es |
dc.date.accessioned | 2020-12-21T20:56:17Z | - |
dc.date.available | 2020-12-21T20:56:17Z | - |
dc.date.issued | 2015-08 | - |
dc.identifier.issn | 0147-9571 | - |
dc.identifier.uri | http://sgc.anlis.gob.ar/handle/123456789/1969 | - |
dc.description | Fil: Sahaza, Jorge H. Laboratorio de Inmunología de Hongos, Unidad de Micología, Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM); México. | es |
dc.description | Fil: Suárez-Alvarez, Roberto. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Micología; Argentina. | es |
dc.description | Fil: Estrada-Bárcenas, Daniel Alfonso. Laboratorio de Inmunología de Hongos, Unidad de Micología, Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM); México. | es |
dc.description | Fil: Pérez-Torres, Armando. Laboratorio de Filogenia del Sistema Inmune de Piel y Mucosas, Departamento de Biología Celular y Tisular, Facultad de Medicina, UNAM; México. | es |
dc.description | Fil: Taylor, Maria Lucia. Laboratorio de Inmunología de Hongos, Unidad de Micología, Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM); México. | es |
dc.description.abstract | The host pulmonary response to the fungus Histoplasma capsulatum was evaluated, through the profile of cytokines detected by the MagPix magnetic beads platform in lung homogenates and by lung-granulomas formation, from mice intra-nasally infected with mycelial propagules (M-phase) of two virulent H. capsulatum strains, EH-46 and G-217B. Results highlight that mice lung inflammatory response depends on the H. capsulatum strain used, during the first step of the fungal infection. IL-1β and TNF-α increased their concentrations in mice infected with both strains. The highest levels of IL-6, IL-17, and IL-23 were found in EH-46-infected mice, whereas levels of IL-22 were variable at all post-infection times for both strains. Significant increases of IL-12, IFN-γ, IL-4, and IL-10 were associated to EH-46-infected mice. Histological lung findings from EH-46-infected mice revealed incipient and numerous well-developed granulomas, distributed in lung-lobes at the 14th and the 21st days after infection, according to cytokine profiles. | es |
dc.language.iso | en | es |
dc.publisher | Elsevier | es |
dc.relation.ispartof | Comparative immunology, microbiology and infectious diseases | es |
dc.rights | Closed Access | - |
dc.source | Comparative Immunology, Microbiology and Infectious Diseases 2015; 41:1-9. | - |
dc.subject | Pulmón | es |
dc.subject | Citocinas | es |
dc.subject | Histoplasma | es |
dc.title | Profile of cytokines in the lungs of BALB/c mice after intra-nasal infection with Histoplasma capsulatum mycelial propagules | es |
dc.type | Artículo | es |
dc.identifier.doi | 10.1016/j.cimid.2015.05.003 | - |
anlis.essnrd | 1 | - |
item.grantfulltext | none | - |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.openairetype | Artículo | - |
Appears in Collections: | Publicaciones INEI |
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