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|Title:||Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study||Authors:||Caini, Saverio
Huang, Q Sue
Ciblak, Meral A
Kusznierz, Gabriela F.
Henriques, Cláudio M P
Fasce, Rodrigo A
Clara, Alexey W
Kadjo, Hervé A
Emukule, Gideon O
Ang, Li Wei
Mai, Le Thi Quynh
|Keywords:||Estudio Global de Influenza B (GIBS);Carga de enfermedad;Epidemiología;Gripe Humana;Vacunación;vaccine mismatch||Issue Date:||Aug-2015||Journal:||Influenza and other respiratory viruses||Abstract:||
INTRODUCTION: Literature on influenza focuses on influenza A, despite influenza B having a large public health impact. The Global Influenza B Study aims to collect information on global epidemiology and burden of disease of influenza B since 2000.
METHODS: Twenty-six countries in the Southern (n = 5) and Northern (n = 7) hemispheres and intertropical belt (n = 14) provided virological and epidemiological data. We calculated the proportion of influenza cases due to type B and Victoria and Yamagata lineages in each country and season; tested the correlation between proportion of influenza B and maximum weekly influenza-like illness (ILI) rate during the same season; determined the frequency of vaccine mismatches; and described the age distribution of cases by virus type.
RESULTS: The database included 935 673 influenza cases (2000-2013). Overall median proportion of influenza B was 22·6%, with no statistically significant differences across seasons. During seasons where influenza B was dominant or co-circulated (>20% of total detections), Victoria and Yamagata lineages predominated during 64% and 36% of seasons, respectively, and a vaccine mismatch was observed in ≈25% of seasons. Proportion of influenza B was inversely correlated with maximum ILI rate in the same season in the Northern and (with borderline significance) Southern hemispheres. Patients infected with influenza B were usually younger (5-17 years) than patients infected with influenza A.
CONCLUSION: Influenza B is a common disease with some epidemiological differences from influenza A. This should be considered when optimizing control/prevention strategies in different regions and reducing the global burden of disease due to influenza.
|Appears in Collections:||Publicaciones INER|
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