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http://sgc.anlis.gob.ar/handle/123456789/392| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.contributor.author | Martin, Valentina | - |
| dc.contributor.author | Arcavi, Miriam | - |
| dc.contributor.author | Santillan, Graciela | - |
| dc.contributor.author | Amendoeira, María Regina R. | - |
| dc.contributor.author | De Souza Neves, Elizabeth | - |
| dc.contributor.author | Griemberg, Gloria | - |
| dc.contributor.author | Guarnera, Eduardo | - |
| dc.contributor.author | Garberi, Juan C. | - |
| dc.contributor.author | Angel, Sergio O. | - |
| dc.date.accessioned | 2012-11-23T03:59:16Z | - |
| dc.date.available | 2012-11-23T03:59:16Z | - |
| dc.date.issued | 1998 | - |
| dc.identifier.issn | 1098-6588 | - |
| dc.identifier.uri | http://sgc.anlis.gob.ar/handle/123456789/392 | - |
| dc.identifier.uri | http://cdli.asm.org/content/5/5/627.full.pdf+html | - |
| dc.description | The Toxoplasma gondii rhoptry protein Rop2 was expressed in Escherichia coli as a fusion protein containing 44 kDa of the 55-kDa mature Rop2, supplied with six histidyl residues at the N-terminal end (Rop2196-561). Humoral response during Toxoplasma infection of humans was analyzed by immunoglobulin G (IgG), IgA, and IgM enzyme-linked immunosorbent assay with Rop2196-561 as the antigen substrate. The analyzed sera were divided according to T. gondii-specific serological tests (IgG, IgA, or IgM indirect immunofluorescence and IgA or IgM immunosorbent agglutination assay) as group A (IgG+ IgA- IgM-; n = 35), group B (IgG+ IgA+ IgM+; n = 21), group C (IgG+ IgA+ IgM-; n = 5), and group D (IgG+ IgA- IgM+; n = 16). Twenty-six T. gondii-seronegative sera from individuals with other infections were also included (group E). Anti-Rop2 IgG antibodies were detected in 82.8% of group A sera and in 97.6% of the sera with acute-phase marker immunoglobulins (groups B, C, and D). The percentage of IgA antibody reactivity against Rop2196-561 was 17.1% in group A, 50% in group D, and 80.8% in groups B and C. The percentage of IgM antibody reactivity was 0% in groups A and C and 62% in groups B and D. Sera from group E failed to show IgA, IgM, or IgG antibody reactivity. Since T. gondii Rop2 elicits a strong humoral response from an early stage of infection, it is suggested that recombinant Rop2196-561 would be suitable for use in diagnostic systems, in combination with other T. gondii antigens, to detect specific IgG, IgA, and IgM antibodies. | ES |
| dc.description | Fil: Martin, Valentina. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Parasitología; Argentina. | ES |
| dc.description | Fil: Arcavi, Miriam. Universidad de Buenos Aires. Immunología Clínica; Argentina. | ES |
| dc.description | Fil: Santillan, Graciela. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Parasitología; Argentina. | ES |
| dc.description | Fil: Amendoeira, María Regina R. Fundaçao Oswaldo Cruz. Instituto Oswaldo Cruz; Brazil. | ES |
| dc.description | Fil: De Souza Neves, Elizabeht. Hospital Evandro Chagas-FIOCRUZ; Brazil. | ES |
| dc.description | Fil: Griemberg, Gloria. Universidad de Buenos Aires. Immunología Clínica; Argentina. | ES |
| dc.description | Fil: Guarnera, Eduardo. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Parasitología; Argentina. | ES |
| dc.description | Fil: Garberi, Juan C. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Parasitología; Argentina. | ES |
| dc.description | Fil: Angel, Sergio O. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Parasitología; Argentina. | ES |
| dc.format | application/pdf | ES |
| dc.language.iso | eng | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.source | Clinical and Diagnostic Laboratory Immunology, 1998, 5(5), 627-631. | en_US |
| dc.subject | Toxoplasmosis | en_US |
| dc.subject | Humanos | en_US |
| dc.subject | Inmunoglobulina A | en_US |
| dc.subject | Inmunoglobulina M | en_US |
| dc.subject | Inmunoglobulina G | en_US |
| dc.title | Detection of human Toxoplasma-specific immunoglobulins A, M, and G with a recombinant Toxoplasma gondii rop2 protein | en_US |
| dc.type | Artículo | es |
| anlis.essnrd | 1 | es |
| item.grantfulltext | open | - |
| item.fulltext | With Fulltext | - |
| item.cerifentitytype | Publications | - |
| item.openairetype | Artículo | - |
| item.languageiso639-1 | en | - |
| item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
| crisitem.author.dept | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
| crisitem.author.dept | Instituto Nacional de Enfermedades Infecciosas (INEI) | - |
| crisitem.author.dept | Departamento de Parasitología | - |
| crisitem.author.dept | Maestría en Microbiología Molecular UNSM-ANLIS | - |
| crisitem.author.dept | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
| crisitem.author.dept | Instituto Nacional de Parasitología (INP) | - |
| crisitem.author.parentorg | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
| crisitem.author.parentorg | Instituto Nacional de Enfermedades Infecciosas (INEI) | - |
| crisitem.author.parentorg | Centro Nacional Red de Laboratorios (CNRL) | - |
| crisitem.author.parentorg | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
| Aparece en las colecciones: | snrd Publicaciones INEI | |
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| ClinicalandDiagnosticLaboratoryImmunology,1998,5(5),627-631..pdf | 173.95 kB | Adobe PDF |  Visualizar/Abrir |
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