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DC Field | Value | Language |
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dc.contributor.author | Viboud, Gloria I. | es |
dc.contributor.author | Jouve, Mabel J. | es |
dc.contributor.author | Binsztein, Norma | es |
dc.contributor.author | Vergara, Marta | es |
dc.contributor.author | Rivas, Marta | es |
dc.contributor.author | Quiroga, Marina | es |
dc.contributor.author | Svennerholm, Ann-Mari | es |
dc.date.accessioned | 2012-11-04T17:58:08Z | - |
dc.date.available | 2012-11-04T17:58:08Z | - |
dc.date.issued | 1999-09 | - |
dc.identifier.issn | 1098-660X | - |
dc.identifier.uri | http://sgc.anlis.gob.ar/handle/123456789/306 | - |
dc.identifier.uri | http://jcm.asm.org/content/37/9/2829.full.pdf+html | - |
dc.description | Fil: Viboud, Gloria I. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología; Argentina. | es |
dc.description | Fil: Jouve, Mabel J. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología; Argentina. | es |
dc.description | Fil: Binsztein, Norma. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología; Argentina. | es |
dc.description | Fil: Vergara, Marta. Universidad Nacional de Misiones. Cátedra de Bacteriología; Argentina. | es |
dc.description | Fil: Rivas, Marta. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología; Argentina. | es |
dc.description | Fil: Quiroga, Marina. Universidad Nacional de Misiones. Cátedra de Bacteriología; Argentina. | es |
dc.description | Fil: Svennerholm, Ann-Mari. University of Göteborg. Department of Medical Microbiology and Immunology; Suiza. | es |
dc.description.abstract | In a follow-up study, enterotoxigenic Escherichia coli (ETEC) infections in 145 children from two communities located in northeastern Argentina were monitored for 2 years. The occurrence of diarrhea was monitored by weekly household visits. Of 730 fecal specimens collected, 137 (19%) corresponded to diarrheal episodes. ETEC was isolated from a significantly higher proportion of symptomatic (18.3%) than asymptomatic (13.3%) children (P 5 0.04541). Individuals of up to 24 months of age were found to have a higher risk of developing ETEC diarrhea than older children (odds ratio [OR], 3.872; P 5 0.00021). When the toxin profiles were considered, only heat stable enterotoxin (ST)-producing ETEC was directly associated with diarrhea (P 5 0.00035). Fifty-five percent of the ETEC isolated from symptomatic children and 19% of the ETEC isolated from asymptomatic children expressed one of the colonization factors (CFs) investigated, i.e., CF antigen I (CFA/I), CFA/II, CFA/III, and CFA/IV; coli surface antigens CS7 and CS17; and putative CFs PCFO159, PCFO166, and PCFO20, indicating a clear association between diarrhea and ETEC strains that carry these factors (P 5 0.0000034). The most frequently identified CFs were CFA/IV (16%), CFA/I (10%), and CS17 (9%). CFs were mostly associated with ETEC strains that produce ST and both heat-labile enterotoxin and ST. Logistic regression analysis, applied to remove confounding effects, revealed that the expression of CFs was associated with illness independently of the toxin type (OR, 4.81; P 5 0.0003). When each CF was considered separately, CS17 was the only factor independently associated with illness (OR, 16.6; P 5 0.0151). Most CFs (the exception was CFA/IV) fell within a limited array of serotypes, while the CF-negative isolates belonged to many different O:H types. These results demonstrate that some CFs are risk factors for the development of ETEC diarrhea. | es |
dc.format | application/pdf | ES |
dc.language.iso | en | es |
dc.publisher | American Society for Microbiology | es |
dc.relation.ispartof | Journal of clinical microbiology | es |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.rights | Creative Commons Attribution 4.0 International License | - |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Journal of Clinical Microbiology 1999; 37(9): 2829–2833. | en_US |
dc.subject | Infecciones por Escherichia coli | es |
dc.subject | Estudios de Cohortes | es |
dc.subject | Lactante | es |
dc.subject | Argentina | es |
dc.subject | Escherichia coli | es |
dc.title | Prospective Cohort Study of Enterotoxigenic Escherichia coli Infections in Argentinean Children | es |
dc.type | Artículo | es |
dc.coverage | ARG | en_US |
dc.identifier.doi | 10.1128/JCM.37.9.2829-2833.1999 | - |
anlis.essnrd | 1 | es |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.openairetype | Artículo | - |
item.fulltext | With Fulltext | - |
item.languageiso639-1 | en | - |
crisitem.author.dept | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
crisitem.author.dept | Instituto Nacional de Enfermedades Infecciosas (INEI) | - |
crisitem.author.dept | Departamento de Bacteriología | - |
crisitem.author.dept | Servicio de Fisiopatogenia | - |
crisitem.author.parentorg | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
crisitem.author.parentorg | Instituto Nacional de Enfermedades Infecciosas (INEI) | - |
crisitem.author.parentorg | Departamento de Bacteriología | - |
Appears in Collections: | snrd Publicaciones INEI |
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File | Description | Size | Format | |
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JournalofClinicalMicrobiology,1999,37(9),2829–2833..pdf | Artículo en inglés | 74.95 kB | Adobe PDF | View/Open |
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