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dc.contributor.authorLevis, Silvana-
dc.contributor.authorGarcia, Jorge-
dc.contributor.authorPini, Noemí-
dc.contributor.authorCalderón, Gladys-
dc.contributor.authorRamírez, Josefina-
dc.contributor.authorBravo, Daniel-
dc.contributor.authorSt. Jeor, Stephen-
dc.contributor.authorRipoll, Carlos-
dc.contributor.authorBego, Mariana-
dc.contributor.authorLozano, Elena-
dc.contributor.authorBarquez, Rubén-
dc.contributor.authorKsiazek, Thomas G.-
dc.contributor.authorEnria, Delia-
dc.date.accessioned2012-10-20T21:42:31Z-
dc.date.available2012-10-20T21:42:31Z-
dc.date.issued2004-
dc.identifier.issn1476-1645-
dc.identifier.urihttp://www.ajtmh.org/content/71/5/658.full.pdf+html-
dc.identifier.urihttp://sgc.anlis.gob.ar/handle/123456789/242-
dc.descriptionThe purpose of this study was to characterize the hantaviruses circulating in northwestern Argentina. Human and rodent studies were conducted in Yuto, where most cases of hantavirus pulmonary syndrome (HPS) occur. Partial virus genome sequences were obtained from the blood of 12 cases of HPS, and from the lungs of 4 Calomys callosus and 1 Akodon simulator. Phylogenetic analysis showed that three genotypes associated with HPS circulate in Yuto. Laguna Negra (LN) virus, associated with C. laucha in Paraguay, was identified for the first time in Argentina; it was recovered from human cases and from C. callosus samples. The high sequence identity between human and rodent samples implicated C. callosus as the primary rodent reservoir for LN virus in Yuto. The genetic analysis showed that the Argentinian LN virus variant differed 16.8% at the nucleotide level and 2.9% at the protein level relative to the Paraguayan LN virus. The other two hantavirus lineages identified were the previously known Bermejo and Orán viruses.en_US
dc.descriptionFil: Levis, Silvana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas Dr. Julio Maiztegui; Argentina.en_US
dc.descriptionFil: Garcia, Jorge. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas Dr. Julio Maiztegui; Argentina.en_US
dc.descriptionFil: Pini, Noemí. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas Dr. Julio Maiztegui; Argentina.en_US
dc.descriptionFil: Calderón, Gladys. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas Dr. Julio Maiztegui; Argentina.en_US
dc.descriptionFil: Ramírez, Josefina. Hospital San Miguel; Argentina.en_US
dc.descriptionFil: Bravo, Daniel. Hospital Oscar Orías; Argentina.en_US
dc.descriptionFil: St. Jeor, Stephen. University of Nevada. Department of Microbiology; Estados Unidos.en_US
dc.descriptionFil: Ripoll, Carlos. Dirección de Epidemiología. San Salvador de Jujuy, Jujuy; Argentina.en_US
dc.descriptionFil: Bego, Mariana. University of Nevada. Department of Microbiology; Estados Unidos.en_US
dc.descriptionFil: Lozano, Elena. Hospital San Miguel; Argentina.en_US
dc.descriptionFil: Barquez, Rubén. Fundación Miguel Lillo; Argentina.en_US
dc.descriptionFil: Ksiazek, Thomas G. Centers for Disease Control and Prevention. Special Pathogens Branch; Estados Unidos.en_US
dc.descriptionFil: Enria, Delia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas Dr. Julio Maiztegui; Argentina.en_US
dc.formatapplication/pdfES
dc.language.isoengen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.sourceThe American Journal of Tropical Medicine and Hygiene, 2004, 71(5), 658–663.en_US
dc.subjectHantavirusen_US
dc.subjectSíndrome Pulmonar por Hantavirusen_US
dc.subjectFilogeniaen_US
dc.subjectRatasen_US
dc.subjectReacción en Cadena de la Polimerasa de Transcriptasa Inversaen_US
dc.subjectARN Viralen_US
dc.subjectRoedoresen_US
dc.subjectHumanosen_US
dc.subjectArgentinaen_US
dc.titleHantavirus pulmonary syndrome in northwestern Argentina : circulation of Laguna Negra virus associated with Calomys callosusen_US
dc.typeArtículoes
dc.coverageARGen_US
anlis.essnrd1es
item.grantfulltextopen-
item.cerifentitytypePublications-
item.fulltextWith Fulltext-
item.languageiso639-1en-
item.openairetypeArtículo-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
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