Please use this identifier to cite or link to this item:
http://sgc.anlis.gob.ar/handle/123456789/218
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Petroni, Alejandro | es |
dc.contributor.author | Corso, Alejandra | es |
dc.contributor.author | Melano, Roberto | es |
dc.contributor.author | Cacace, María Luisa | es |
dc.contributor.author | Bru, Ana María | es |
dc.contributor.author | Rossi, Alicia | es |
dc.contributor.author | Galas, Marcelo F. | es |
dc.date.accessioned | 2012-10-18T03:55:01Z | - |
dc.date.available | 2012-10-18T03:55:01Z | - |
dc.date.issued | 2002-05 | - |
dc.identifier.issn | 1098-6596 | - |
dc.identifier.uri | http://sgc.anlis.gob.ar/handle/123456789/218 | - |
dc.description | Fil: Petroni, Alejandro. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Servicio de Antimicrobianos; Argentina. | es |
dc.description | Fil: Corso, Alejandra. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Servicio de Antimicrobianos; Argentina. | es |
dc.description | Fil: Melano, Roberto. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Servicio de Antimicrobianos; Argentina. | es |
dc.description | Fil: Cacace, María Luisa. Hospital San Vicente de Paul; Argentina. | es |
dc.description | Fil: Bru, Ana María. Hospital Juan D. Perón; Argentina. | es |
dc.description | Fil: Rossi, Alicia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Servicio de Antimicrobianos; Argentina. | es |
dc.description | Fil: Galas, Marcelo F. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Servicio de Antimicrobianos; Argentina. | es |
dc.description.abstract | Since 1992 there have been seven major outbreaks of cholera in Argentina. Susceptibility analysis of 1,947 isolates (40% of reported cases) of Vibrio cholerae O1 biotype El Tor suggested the presence of extended-spectrum beta-lactamases (ESBLs) in 28 isolates. Because of their different susceptibility profiles, V. cholerae isolates M1502, M1516, M1573, and M3030 (all of which are of the Ogawa serotype) were selected for the present study. By susceptibility analysis, isoelectric focusing, and PCR-based restriction fragment length polymorphism analysis, CTX-M-type enzymes were identified in three isolates, whereas a PER-2-type enzyme, in addition to a TEM-1-like enzyme, was identified in the other isolate. The presence of these ESBLs in V. cholerae isolates resulted in MICs well below those commonly observed for members of the family ENTEROBACTERIACEAE: Genes that encode both ESBLs were transferred to Escherichia coli by conjugation, together with all determinants of resistance to non-beta-lactam antibiotics (gentamicin, kanamycin, and sulfamethoxazole for all isolates; amikacin and streptomycin for three isolates; trimethoprim, tetracycline, and chloramphenicol for two isolates). Plasmid profile analysis and Southern blotting revealed the presence of single plasmids of about 150 kb in the four V. cholerae isolates and their respective transconjugants and revealed that the plasmids harbored genes encoding CTX-M-type or PER-2-type ESBLs. These results strongly suggest the broad spread of these ESBLs among genera belong to families other than the ENTEROBACTERIACEAE: | es |
dc.format | ES | |
dc.language.iso | en | es |
dc.relation.ispartof | Antimicrobial agents and chemotherapy | es |
dc.rights | Open Access | en_US |
dc.rights | Creative Commons Attribution 4.0 International License | - |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Antimicrobial Agents and Chemotherapy 2002;46(5):1462–1468 | en_US |
dc.subject | Cólera | es |
dc.subject | Brotes de Enfermedades | es |
dc.subject | Farmacorresistencia Bacteriana | es |
dc.subject | beta-Lactamasas | es |
dc.subject | Focalización Isoeléctrica | es |
dc.subject | Plásmidos | es |
dc.subject | Vibrio cholerae | es |
dc.subject | Argentina | es |
dc.title | Plasmidic extended-spectrum beta-lactamases in Vibrio cholerae O1 El Tor isolates in Argentina | es |
dc.type | Artículo | es |
dc.coverage | ARG | en_US |
dc.identifier.doi | 10.1128/aac.46.5.1462-1468.2002 | - |
anlis.essnrd | 1 | es |
item.openairetype | Artículo | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | With Fulltext | - |
crisitem.author.dept | Servicio Antimicrobianos | - |
crisitem.author.dept | Departamento de Bacteriología | - |
crisitem.author.dept | Instituto Nacional de Enfermedades Infecciosas (INEI) | - |
crisitem.author.dept | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
crisitem.author.dept | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
crisitem.author.dept | Instituto Nacional de Enfermedades Infecciosas (INEI) | - |
crisitem.author.dept | Departamento de Bacteriología | - |
crisitem.author.dept | Servicio Antimicrobianos | - |
crisitem.author.dept | Public Health Ontario Laboratory | - |
crisitem.author.dept | Maestría en Microbiología Molecular UNSM-ANLIS | - |
crisitem.author.dept | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
crisitem.author.dept | Instituto Nacional de Enfermedades Infecciosas (INEI) | - |
crisitem.author.orcid | 0000-0003-1177-7037 | - |
crisitem.author.parentorg | Departamento de Bacteriología | - |
crisitem.author.parentorg | Instituto Nacional de Enfermedades Infecciosas (INEI) | - |
crisitem.author.parentorg | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
crisitem.author.parentorg | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
crisitem.author.parentorg | Instituto Nacional de Enfermedades Infecciosas (INEI) | - |
crisitem.author.parentorg | Departamento de Bacteriología | - |
crisitem.author.parentorg | Centro Nacional Red de Laboratorios (CNRL) | - |
crisitem.author.parentorg | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
Appears in Collections: | snrd Publicaciones INEI |
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File | Description | Size | Format | |
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AntimicrobialAgentsandChemotherapy_2002_46_5_p1462–p1468.pdf | 107.63 kB | Adobe PDF | View/Open |
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