Please use this identifier to cite or link to this item:
http://sgc.anlis.gob.ar/handle/123456789/2121
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Altcheh, Jaime | es |
dc.contributor.author | Diaz, N | es |
dc.contributor.author | Pepe, Carolina M | es |
dc.contributor.author | Martín, Valentina | es |
dc.contributor.author | Nigro, Monica | es |
dc.contributor.author | Freilij, Héctor | es |
dc.contributor.author | Angel, Sergio O. | es |
dc.date.accessioned | 2021-01-13T00:45:52Z | - |
dc.date.available | 2021-01-13T00:45:52Z | - |
dc.date.issued | 2006-10 | - |
dc.identifier.issn | 0732-8893 | - |
dc.identifier.uri | http://sgc.anlis.gob.ar/handle/123456789/2121 | - |
dc.description | Fil: Altcheh, Jaime. Hospital de Niños Dr. Ricardo Gutiérrez. Parasitología; Argentina. | es |
dc.description | Fil: Diaz, Natalia S. Hospital de Niños Dr. Ricardo Gutiérrez. Parasitología; Argentina. | es |
dc.description | Fil: Pepe, Carolina M. Hospital de Niños Dr. Ricardo Gutiérrez. Parasitología; Argentina. | es |
dc.description | Fil: Martin, Valentina. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Parasitología; Argentina. | es |
dc.description | Fil: Nigro, Monica. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Parasitología; Argentina. | es |
dc.description | Fil: Freilij, Héctor. Hospital de Niños Dr. Ricardo Gutiérrez. Parasitología; Argentina. | es |
dc.description | Fil: Angel, Sergio O. CONICET-UNSAM. Laboratorio de Parasitología Molecular, Chascomús; Argentina. | es |
dc.description.abstract | The reactivity values of Toxoplasma gondii ROP2, GRA4, and GRA7 recombinant antigens (rAgs) were analyzed by immunoglobulin G (IgG) enzyme-linked immunosorbent assay (ELISA) in 23 congenitally infected (I) and 36 noninfected (NI) infants. The reactivity values observed from the serum samples of I versus NI infants for each recombinant protein were 91% versus 67% for rROP2 (P = .05), 86% versus 29% for rGRA4 (P < .001), and 56% versus 11% for rGRA7 (P = .003). The follow-up showed that serum samples from NI infants became negative for specific IgG at 5.8 months (95% confidence interval [CI], 4.9-6.7) using a commercial assay; meanwhile, by specific recombinant protein ELISA, the samples became negative at 3.7 months with rROP2 (95% CI, 2.8-4.6), at 1.3 months with rGRA4 (95% CI, 0.8-1.8), and at 0.9 months with rGRA7 (95% CI, 0.5-1.3). Kinetic analysis also showed that serum samples from group I presented different IgG-profiles among rAgs. The rROP2 IgG profile was similar to that of the commercial assay, whereas rGRA4 and rGRA7 profiles showed a gradual decrease along the period of the study. The potential of the utility of rAgs to develop a diagnostic system that discriminates congenitally I infants from NI is discussed. | es |
dc.format | - | |
dc.language.iso | en | es |
dc.relation.ispartof | Diagnostic microbiology and infectious disease | es |
dc.rights | Closed Access | - |
dc.source | Diagnostic Microbiology and Infectious Disease 2006;56(2):161-165 | - |
dc.subject | Toxoplasma | es |
dc.subject | Toxoplasmosis Congénita | es |
dc.subject | Etanercept | es |
dc.subject | Diagnóstico | es |
dc.title | Kinetic analysis of the humoral immune response against 3 Toxoplasma gondii-recombinant proteins in infants with suspected congenital toxoplasmosis | es |
dc.type | Artículo | es |
dc.identifier.doi | 10.1016/j.diagmicrobio.2006.03.012 | - |
anlis.essnrd | 1 | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.openairetype | Artículo | - |
item.fulltext | No Fulltext | - |
item.languageiso639-1 | en | - |
Appears in Collections: | Publicaciones INEI |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.