Please use this identifier to cite or link to this item:
http://sgc.anlis.gob.ar/handle/123456789/1724
DC Field | Value | Language |
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dc.contributor.author | Deluca, G D | es |
dc.contributor.author | Marin, H M | es |
dc.contributor.author | Blanco, N S | es |
dc.contributor.author | Basiletti, J A | es |
dc.contributor.author | González, J V | es |
dc.contributor.author | Merino, A L | es |
dc.contributor.author | Picconi, María Alejandra | es |
dc.date.accessioned | 2020-11-24T16:47:32Z | - |
dc.date.available | 2020-11-24T16:47:32Z | - |
dc.date.issued | 2013-04 | - |
dc.identifier.uri | http://sgc.anlis.gob.ar/handle/123456789/1724 | - |
dc.description | Fil: Deluca, G. D. Northeast National University. Faculty of Medicine. Department of Clinical Microbiology. Laboratory of Molecular Application; Argentina. | es |
dc.description | Fil: Marin, H. M. Northeast National University. Institute of Regional Medicine. Department of Virology. Laboratory of Molecular Biology; Argentina. | es |
dc.description | Fil: Blanco, N. S. Northeast National University. Faculty of Medicine. Department of Clinical Microbiology. Laboratory of Molecular Application; Argentina. | es |
dc.description | Fil: Basiletti, J. A. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina. | es |
dc.description | Fil: González, J. V. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina. | es |
dc.description | Fil: Merino, A. L. Northeast National University. Faculty of Medicine. Department of Clinical Microbiology. Laboratory of Molecular Application; Argentina. | es |
dc.description | Fil: Picconi, M. A. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina. | es |
dc.description.abstract | Background: Cervical cancer remains a major public health problem in northern Argentina, showing the highest mortality rate in the country (approximately 22 cases/100000 women). Objective: The aim of this study was to provide epidemiological data on the prevalence and type distribution of human papillomavirus (HPV) in women with pre-neoplastic lesions before the massive introduction of HPV vaccination in the country. Materials and methods: Exfoliated cervical cells were collected to screen for HPV using the widely known MY09/11 PCR, followed by the restriction fragment-length polymorphism (RFLP) technique from a total of 714 women with previously diagnosed atypical squamous cells of undetermined significance (ASCUS), low-grade squamous intraepithelial lesion (LG-SIL) and high-grade squamous intraepithelial lesion (HG-SIL). Results: Overall HPV prevalence was 48.2% in ASCUS (24 different HPV types detected), 66.5% in LG-SIL (37 HPV types detected) and 82.6% in HG-SIL (16 HPV types detected). HPV-16 was the most prevalent type among all cases. With respect to multiple HPV infections, 9.6% were observed in ASCUS, 14.3% in LG-SIL and 11.4% in HG-SIL. Conclusion: The major strength of our study is the assessment of a large series of women with cytological alterations in this region. The information attained will be useful as a regional baseline for future epidemiological vigilance, in the context of the national HPV vaccination program. | es |
dc.language.iso | en | es |
dc.publisher | Medknow Publications | es |
dc.relation | datasets | es |
dc.relation.ispartof | Indian journal of medical microbiology | es |
dc.rights | Open Access | - |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Indian Journal of Medical Microbiology 2013; 31(2):138-141 | - |
dc.subject | Adolescente | es |
dc.subject | Adulto | es |
dc.subject | Anciano | es |
dc.subject | Argentina | es |
dc.subject | ADN Viral | es |
dc.subject | Genotipo | es |
dc.subject | Humanos | es |
dc.subject | Persona de Mediana Edad | es |
dc.subject | Epidemiología Molecular | es |
dc.subject | Papillomaviridae | es |
dc.subject | Infecciones por Papillomavirus | es |
dc.subject | Reacción en Cadena de la Polimerasa | es |
dc.subject | Polimorfismo de Longitud del Fragmento de Restricción | es |
dc.subject | Prevalencia | es |
dc.subject | Neoplasias del Cuello Uterino | es |
dc.subject | Adulto Joven | es |
dc.title | Distribution of human papillomavirus genotypes in women with cervical alterations from north Argentina | es |
dc.type | Artículo | es |
dc.rights.license | Creative Commons Attribution 4.0 International License | - |
dc.identifier.doi | 10.4103/0255-0857.115228 | - |
anlis.essnrd | 1 | - |
item.fulltext | No Fulltext | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.openairetype | Artículo | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
crisitem.author.dept | Instituto Nacional de Enfermedades Infecciosas (INEI) | - |
crisitem.author.dept | Departamento de Virología | - |
crisitem.author.dept | Servicio Virus Oncogénicos | - |
crisitem.author.dept | Maestría en Microbiología Molecular UNSM-ANLIS | - |
crisitem.author.dept | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
crisitem.author.dept | Instituto Nacional de Enfermedades Infecciosas (INEI) | - |
crisitem.author.dept | Departamento de Virología | - |
crisitem.author.dept | Servicio Virus Oncogénicos | - |
crisitem.author.parentorg | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
crisitem.author.parentorg | Instituto Nacional de Enfermedades Infecciosas (INEI) | - |
crisitem.author.parentorg | Departamento de Virología | - |
crisitem.author.parentorg | Centro Nacional Red de Laboratorios (CNRL) | - |
crisitem.author.parentorg | Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS) | - |
crisitem.author.parentorg | Instituto Nacional de Enfermedades Infecciosas (INEI) | - |
crisitem.author.parentorg | Departamento de Virología | - |
Appears in Collections: | Publicaciones INEI |
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