Please use this identifier to cite or link to this item: http://sgc.anlis.gob.ar/handle/123456789/1724
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dc.contributor.authorDeluca, G Des
dc.contributor.authorMarin, H Mes
dc.contributor.authorBlanco, N Ses
dc.contributor.authorBasiletti, J Aes
dc.contributor.authorGonzález, J Ves
dc.contributor.authorMerino, A Les
dc.contributor.authorPicconi, María Alejandraes
dc.date.accessioned2020-11-24T16:47:32Z-
dc.date.available2020-11-24T16:47:32Z-
dc.date.issued2013-04-
dc.identifier.urihttp://sgc.anlis.gob.ar/handle/123456789/1724-
dc.descriptionFil: Deluca, G. D. Northeast National University. Faculty of Medicine. Department of Clinical Microbiology. Laboratory of Molecular Application; Argentina.es
dc.descriptionFil: Marin, H. M. Northeast National University. Institute of Regional Medicine. Department of Virology. Laboratory of Molecular Biology; Argentina.es
dc.descriptionFil: Blanco, N. S. Northeast National University. Faculty of Medicine. Department of Clinical Microbiology. Laboratory of Molecular Application; Argentina.es
dc.descriptionFil: Basiletti, J. A. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.es
dc.descriptionFil: González, J. V. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.es
dc.descriptionFil: Merino, A. L. Northeast National University. Faculty of Medicine. Department of Clinical Microbiology. Laboratory of Molecular Application; Argentina.es
dc.descriptionFil: Picconi, M. A. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.es
dc.description.abstractBackground: Cervical cancer remains a major public health problem in northern Argentina, showing the highest mortality rate in the country (approximately 22 cases/100000 women). Objective: The aim of this study was to provide epidemiological data on the prevalence and type distribution of human papillomavirus (HPV) in women with pre-neoplastic lesions before the massive introduction of HPV vaccination in the country. Materials and methods: Exfoliated cervical cells were collected to screen for HPV using the widely known MY09/11 PCR, followed by the restriction fragment-length polymorphism (RFLP) technique from a total of 714 women with previously diagnosed atypical squamous cells of undetermined significance (ASCUS), low-grade squamous intraepithelial lesion (LG-SIL) and high-grade squamous intraepithelial lesion (HG-SIL). Results: Overall HPV prevalence was 48.2% in ASCUS (24 different HPV types detected), 66.5% in LG-SIL (37 HPV types detected) and 82.6% in HG-SIL (16 HPV types detected). HPV-16 was the most prevalent type among all cases. With respect to multiple HPV infections, 9.6% were observed in ASCUS, 14.3% in LG-SIL and 11.4% in HG-SIL. Conclusion: The major strength of our study is the assessment of a large series of women with cytological alterations in this region. The information attained will be useful as a regional baseline for future epidemiological vigilance, in the context of the national HPV vaccination program.es
dc.language.isoenes
dc.publisherMedknow Publicationses
dc.relationdatasetses
dc.relation.ispartofIndian journal of medical microbiologyes
dc.rightsOpen Access-
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/-
dc.sourceIndian Journal of Medical Microbiology 2013; 31(2):138-141-
dc.subjectAdolescentees
dc.subjectAdultoes
dc.subjectAncianoes
dc.subjectArgentinaes
dc.subjectADN Virales
dc.subjectGenotipoes
dc.subjectHumanoses
dc.subjectPersona de Mediana Edades
dc.subjectEpidemiología Moleculares
dc.subjectPapillomaviridaees
dc.subjectInfecciones por Papillomaviruses
dc.subjectReacción en Cadena de la Polimerasaes
dc.subjectPolimorfismo de Longitud del Fragmento de Restricciónes
dc.subjectPrevalenciaes
dc.subjectNeoplasias del Cuello Uterinoes
dc.subjectAdulto Jovenes
dc.titleDistribution of human papillomavirus genotypes in women with cervical alterations from north Argentinaes
dc.typeArtículoes
dc.rights.licenseCreative Commons Attribution 4.0 International License-
dc.identifier.doi10.4103/0255-0857.115228-
anlis.essnrd1-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.openairetypeArtículo-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptAdministración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS)-
crisitem.author.deptInstituto Nacional de Enfermedades Infecciosas (INEI)-
crisitem.author.deptDepartamento de Virología-
crisitem.author.deptServicio Virus Oncogénicos-
crisitem.author.deptMaestría en Microbiología Molecular UNSM-ANLIS-
crisitem.author.deptAdministración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS)-
crisitem.author.deptInstituto Nacional de Enfermedades Infecciosas (INEI)-
crisitem.author.deptDepartamento de Virología-
crisitem.author.deptServicio Virus Oncogénicos-
crisitem.author.parentorgAdministración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS)-
crisitem.author.parentorgInstituto Nacional de Enfermedades Infecciosas (INEI)-
crisitem.author.parentorgDepartamento de Virología-
crisitem.author.parentorgCentro Nacional Red de Laboratorios (CNRL)-
crisitem.author.parentorgAdministración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS)-
crisitem.author.parentorgInstituto Nacional de Enfermedades Infecciosas (INEI)-
crisitem.author.parentorgDepartamento de Virología-
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